Pharma R&D Today

Ideas and Insight supporting all stages of Drug Discovery & Development

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Bringing Scalability Into Chemistry Modeling

Posted on November 18th, 2020 by

Synthetic chemistry has been with us for centuries, but it is now entering a new frontier. Big data, AI and machine learning are unlocking a predictive power that is transforming the conceptualization and optimization of synthetic routes.

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International Life Science Awards Recognize Reaxys

Posted on November 16th, 2020 by

The International Life Sciences Awards, an initiative from Global Health & Pharma Magazine (GHP) that is now in its fifth year, recognizes industry innovators – and this year that has included honoring Reaxys as an innovation leader by awarding it the Best Chemistry Predictive Analytics Specialists 2020 for its best-in-class Predictive Retrosynthesis software.

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Model-based Strategy to Guide the Choice of Clinical Doses for ADC

Posted on October 14th, 2020 by

Chemotherapy has been a powerful method for fighting cancer for decades. One of the most effective therapies available, it is also known for weakening the patient and causing harsh side effects like pain, nausea, and hair loss. This is because in its zeal to attack cancer cells, chemo also kills healthy cells.

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How DNA-encoded Libraries Boost Drug Discovery

Posted on October 7th, 2020 by

DNA-encoded libraries (DELs) have been gaining a lot of traction in hit finding and drug discovery in recent years. Regarded by some as a truly revolutionary advance in chemistry, a DEL is a mixture of millions of small molecules in which each molecule is conjugated to a DNA-oligomer that encodes its chemical structure. The mixture can be stored in a simple test tube.

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