Pharma R&D Today

Ideas and Insight supporting all stages of Drug Discovery & Development

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Modulators, Biomarkers and Potential Treatments for COVID-19

Posted on May 14th, 2020 by in COVID-19

With the trend of open science, people are becoming more receptive to the idea of sharing data and using what is already accessible. Particularly for researchers, there is so much data available that can answer questions and develop hypotheses and strategies that could save effort, time and money. This is mainly important in cases where rapid discoveries are required, such as in the case of the current COVID-19 outbreak.

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SARS-CoV-2 Vaccine Candidates In or Nearing Clinical Trials

Posted on May 6th, 2020 by in COVID-19

The number of vaccines in the pipeline to battle the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has reached to >70 candidates [1,2]. Many different vaccination strategies are being tested, even a noncoronavirus-specific candidate (Bacille Calmette-Guerin vaccine) [2,3] is being investigated because of its potential to promote a less inflammatory immune response to respiratory pathogens [2]. However, a SARS-Cov-2–specific vaccine will likely be a better strategy.

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Nucleic Acid–Based Vaccines in Development for SARS-CoV-2

Posted on May 1st, 2020 by in COVID-19

With the coronavirus disease 2019 (COVID-19) case and death count climbing [1] despite multiple industry shutdowns and extensive social distancing efforts, it has become clear that a vaccine is required to control the spread of the COVID-19 causative agent, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Many different researchers, institutes and companies specializing in vaccine development across the world have entered the race and announced a candidate, resulting in an astonishingly large number (>70) of vaccines in the pipeline [2,3].

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Mathematical modeling the emergence and spread of new pathogens: Insight for SARS-CoV-2 and other similar viruses

Posted on April 24th, 2020 by in COVID-19

Knowing if and how rapidly an emerging pathogen will spread through a population enables public health officials to make well-informed decisions to protect the public. Mathematical modeling can provide them this means to predict pathogen spread, but modeling previously unheard of pathogens, like severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is challenging.

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