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BCG – COVID-19 Hackathon Challenge Now Extended Through End of Year

Posted on October 23rd, 2020 by in COVID-19

A renewed interest in whether the BCG vaccine (for tuberculosis) could also have an application for COVID-19 has been on the rise, as evidenced by this recent Cell publication, the University of Exeter’s involvement in the BRACE Trial and ongoing general press coverage. Furthermore, the list of clinical trials focusing on this area is continuing to grow (and is available here).

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BCG-COVID 19 Hackathon: Task 1 winners announced, Task 2 – data scientists – we need you!

Posted on September 10th, 2020 by in COVID-19

We’ve seen the scientific community come together time and again throughout the COVID-19 pandemic, and we’re thrilled to have been part of a hackathon bringing together data scientists, epidemiologists and partner organizations focusing on analysing the hypothesis of whether the tuberculosis (TB) vaccine – BCG – could reduce COVID-19 mortality.

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Modeling Coronavirus – Cytokine Storm

Posted on September 4th, 2020 by in COVID-19

Figure 1. Classification of COVID-19 Disease States.
Adapted from Sidiqi, H.K. and M.R. Mehra, COVID-19 Illness in Native and Immunosuppressed States: A Clinical-Therapeutic Staging Proposal. J Heart Lung Transplant, 2020. [1]

(This piece was co-authored by Prof. Gordon Broderick, Clinical Systems Biology at Rochester General Hospital.)

The thing that kills you with coronavirus is not necessarily the infection itself but rather your own body’s response to the infection. Failure to clear the virus with an appropriate immune response can lead to pulmonary symptoms of increasing severity and which can even be fatal in a minority of cases (Figure 1). This late stage of a COVID-19 infection is characterized by a state of hyperinflammation or, as it is more commonly known, a “cytokine storm”.

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Research Data Alliance Releases Guidelines for COVID-19 Data Sharing

Posted on July 24th, 2020 by in COVID-19

The Research Data Alliance (RDA) has released its final version of the RDA COVID-19 Recommendations and Guidelines on data sharing for COVID-19, which covers four main research areas: clinical data, omics practices, epidemiology and social sciences. The document also touches on issues like community participation, legal and ethical considerations, research software and indigenous data.

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