Pharma R&D Today

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Increase visibility of your COVID-19 clinical findings with SSRN

Posted on April 9th, 2020 by in COVID-19

Quickly communicating pertinent clinical information, such as research regarding patient treatments, is critical during public health crises like the ongoing novel coronavirus disease 2019 (COVID-19) pandemic. However, the standard publication process for scientific articles, including peer review, can take as long as two years, and this slow pace of scientific publication can interfere with response to the public health emergency. A faster means for relaying information on COVID-19 research is required.

Fortunately, a more expedient way to disseminate ongoing research information is already available through the use of preprint servers, such as Elsevier’s SSRN. With preprint server publication, research becomes available online pre–peer review for public review and comment as soon as the server verifies certain standards are met (e.g., content is complete, patient privacy was protected). The time taken between article submission and online publication is much faster, typically in the range of hours to days.

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Integration and visualization of COVID-19 molecular mechanisms using Pathway Studio

Posted on April 6th, 2020 by in COVID-19

Integrating the rich information from multi-omics data has been a popular approach to drugs discovery and development against novel 2019 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). To facilitate the integrative analysis and power the global researchers, we have constructed various models that contain biomedical pathways information for SARS-CoV and SARS-CoV-2. Now they are available for public access.

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Analgesics Use and the Coronavirus: Finding Answers Through Biological Knowledge Graph

Posted on March 31st, 2020 by in COVID-19

a. 121 ARDS-induced proteins whose activity and/or abundance are upregulated by ARDS
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Exploring the effectiveness of traditional Chinese medicine against COVID-19

Posted on March 18th, 2020 by in COVID-19

With the continued fatal spread of COVID-19 and no cure at hand, Chinese doctors are looking to pharmaceutical drugs and traditional Chinese medicine (TCM) alike to explore possibilities for treatment as well as prevention. According to Nature, traditional therapies are included among the many clinical trials that are running or pending in China right now. But there is concern that rigorous standards need to be set, to ensure the trial results can be trusted.

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