Pharma R&D Today
Ideas and Insight supporting all stages of Drug Discovery & Development
How DNA-encoded Libraries Boost Drug Discovery
Posted on October 7th, 2020 by Xuanyan Xu in Pharma R&D
DNA-encoded libraries (DELs) have been gaining a lot of traction in hit finding and drug discovery in recent years. Regarded by some as a truly revolutionary advance in chemistry, a DEL is a mixture of millions of small molecules in which each molecule is conjugated to a DNA-oligomer that encodes its chemical structure. The mixture can be stored in a simple test tube.
(more…)Webinar: Accelerating drug discovery by building and turning high-quality data into actionable insights
Posted on April 6th, 2020 by Rosalind Sankey in Chemistry
Drug discovery is a time-consuming and costly process (and all the more costly because it’s time-consuming). One of the hopes of the era of Big Data has been that having access to a wealth of scientific information could help speed the discovery process. However, the data itself has proven to come with many challenges. Medicinal chemists like myself are often frustrated in our attempts to integrate and work with disparate and unstructured sets of data.
(more…)When insights from pharma help fight fungus
Posted on March 24th, 2020 by Maria Shkrob in Pharma R&D
Fungicide resistance is a growing problem, as evidenced by publication trends. Publications on this issue are particularly high across the world’s major economies, and many focus specifically on the fungus Botrytis.
(more…)How can we get pharma R&D to embrace FAIR data?
Posted on January 6th, 2020 by Ani Marrs in Pharma R&D
FAIR data, which is Findable, Accessible, Interoperable and Reusable, has the power to transform the analyses enabling drug discovery and development—yet, the pharma industry has been slow to adopt it. There are a number of reasons for this unfortunate reality, but there is a path to realizing the potential for FAIR data in pharmaceutical R&D.
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