Pharma R&D Today

Ideas and Insight supporting all stages of Drug Discovery & Development

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Proteins behaving badly

Posted on January 5th, 2016 by in Chemistry

The best present I ever received as a child was a game called Mousetrap. For those unlucky enough not to have played this: releasing a lever leads to a series of seemingly random events, such as a boot kicking a ball, and finally to (more…)

Express your “Pharma Pride”, Clearly Communicate Science

Posted on November 23rd, 2015 by in Pharma R&D

Have you ever tried googling ‘Pharma Industry’? Right after Wikipedia, page after page, you will find various articles referring to ‘Getting High on Fat Profits’, ‘Holding Big Pharma Accountable’. (more…)

Using Reaxys for Lead Optimization: A Case Study

Posted on November 13th, 2015 by in Pharma R&D

Epigen Biosciences is a start-up pharmaceutical company that collaborates with academic groups to discover innovative drugs for a range of medical conditions, including renal diseases, cancer and CNS disorders. Co-founder Dr. Fabio Tucci met with Elsevier to discuss how Epigen researchers use Reaxys to support their application of advanced hit-to-lead and lead optimization methods. (more…)

More Drugs, Fewer Patients: Limits of Precision Medicine

Posted on November 9th, 2015 by in Chemistry

A number of targeted medications that are highly effective for a subgroup of patients with a particular disease have emerged in the last decade. These are often needed alternatives to debilitating therapies with uncertain outcomes. The small number of patients that benefit from such therapies, however, may pose a serious challenge looking into the future. (more…)

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