Pharma R&D Today

Ideas and Insight supporting all stages of Drug Discovery & Development

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The Power of Two in Lead Optimization

Posted on July 3rd, 2017 by in Chemistry

The rise of in silico approaches has revolutionized early drug discovery, making it possible to model the potential in vivo behaviors of large numbers of compounds, delve deep into their bioactive and chemical properties, Continue reading “The Power of Two in Lead Optimization” »

The Value of Drug–Drug Interaction Risk Assessments

Posted on June 28th, 2017 by in Pharma R&D

Should a drug candidate move on to pre-clinical and clinical trials? It’s a question that every pharmaceutical developer must face, and the earlier they can answer it, the better in terms of use of time and effort. Continue reading “The Value of Drug–Drug Interaction Risk Assessments” »

Start-up Spotlight: Innovative Informatica Technologies

Posted on November 4th, 2016 by in Pharma R&D

In our data-driven age, bioinformatics companies like Innovative Informatica Technologies have a great deal to offer the industry and boast the potential to do amazing things in drug discovery. Syed Hussain Basha, Founder & CEO of this ambitious start-up, reveals what the company is currently working on.

Continue reading “Start-up Spotlight: Innovative Informatica Technologies” »

Predictions, Modelling and Simulations: Their role in R&D decision-making is more “what” than “how”?

Posted on August 8th, 2016 by in Pharma R&D

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“Predictions are difficult, especially when they are about the future”, a statement attributed to the Noble laurate Niels Bohr is very true.  Despite these difficulties, the Pharma industry has built a range of predictive models to understand a range of drug actions including toxicity, disposition, elimination and efficacy.  Continue reading “Predictions, Modelling and Simulations: Their role in R&D decision-making is more “what” than “how”?” »

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