Pharma R&D Today

Ideas and Insight supporting all stages of Drug Discovery & Development

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The Power of Two in Lead Optimization

Posted on July 3rd, 2017 by in Chemistry

The rise of in silico approaches has revolutionized early drug discovery, making it possible to model the potential in vivo behaviors of large numbers of compounds, delve deep into their bioactive and chemical properties, (more…)

Ensuring the Safety of New Antipsychotics

Posted on October 30th, 2015 by in Chemistry

Antipsychotics have complex pharmacological profiles and adverse events are common with long-term use. New or optimized drugs with better safety profiles are desirable. The best way to get information on a new compound that has potential as an antipsychotic is to use in silico profiling to compare it to existing drugs, as described in this new paper.

Read all about drug safety of new antipsychotics.

Using Intelligent and Connected Taxonomies to Power Insightful Reasearch

Posted on October 27th, 2015 by in Chemistry

Information is useful only when it can be found. Taxonomies offer obvious organizational benefits, but their impact on database usability is far-reaching.
Read an excerpt from the Elsevier whitepaper, The Means to Use Information, to discover how to maximize taxonomies and learn how to utilize intelligent and connected taxonomies to take your insightful research to the next level. (more…)