Pharma R&D Today

Ideas and Insight supporting all stages of Drug Discovery & Development

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Leveling the Playing Field in Medicinal Chemistry

Posted on June 26th, 2017 by in Chemistry

For the designers and developers of Elsevier’s R&D Solutions, a major concern is ensuring that each solution makes the same level of searching or analytical power available to all users. The primary aim for the teams is to Continue reading “Leveling the Playing Field in Medicinal Chemistry” »

Predictive Analytics for Drug Discovery

Posted on September 28th, 2016 by in Pharma R&D

The drive to predict molecular properties and thereby reduce lab testing and focus research projects started before the invention of the computer; a notable advance was with the Hammett equation in the 1930’s.[1]  Continue reading “Predictive Analytics for Drug Discovery” »

Proteins behaving badly

Posted on January 5th, 2016 by in Chemistry

The best present I ever received as a child was a game called Mousetrap. For those unlucky enough not to have played this: releasing a lever leads to a series of seemingly random events, such as a boot kicking a ball, and finally to Continue reading “Proteins behaving badly” »

Eluding a Post-Antibiotic Era: The Challenge of Designing Novel Antibiotics

Posted on November 13th, 2015 by in Pharma R&D

As cases of drug-resistant pathogens multiply, the WHO warns of a “post-antibiotic era.” Designing novel antibiotics, however, remains a scientific challenge because achieving therapeutic efficacy requires painstaking testing of compound properties that often conflict. Continue reading “Eluding a Post-Antibiotic Era: The Challenge of Designing Novel Antibiotics” »