Pharma R&D Today

Ideas and Insight supporting all stages of Drug Discovery & Development

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Predictive Analytics for Drug Discovery

Posted on September 28th, 2016 by in Pharma R&D

The drive to predict molecular properties and thereby reduce lab testing and focus research projects started before the invention of the computer; a notable advance was with the Hammett equation in the 1930’s.[1]  Continue reading “Predictive Analytics for Drug Discovery” »

Proteins behaving badly

Posted on January 5th, 2016 by in Chemistry

The best present I ever received as a child was a game called Mousetrap. For those unlucky enough not to have played this: releasing a lever leads to a series of seemingly random events, such as a boot kicking a ball, and finally to Continue reading “Proteins behaving badly” »

Eluding a Post-Antibiotic Era: The Challenge of Designing Novel Antibiotics

Posted on November 13th, 2015 by in Pharma R&D

As cases of drug-resistant pathogens multiply, the WHO warns of a “post-antibiotic era.” Designing novel antibiotics, however, remains a scientific challenge because achieving therapeutic efficacy requires painstaking testing of compound properties that often conflict. Continue reading “Eluding a Post-Antibiotic Era: The Challenge of Designing Novel Antibiotics” »